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The use of masks is a prevention and control measure that can limit the entry of viruses that attack through the respiratory tract. One of them is Covid-19, masks can be used to protect healthy people. The use of appropriate and correct masks requires the compliance of users, including the elderly who are the most vulnerable group and have a major impact on deaths due to Covid-19 transmission. The research design used is descriptive analytic with a cross sectional approach. The population in this study were the elderly, amounting to 47 people. The sampling technique in this study was a total sampling of 47 people. The results showed that knowledge with a significance value of 0.001 <0.05 and an attitude significance value of 0.004 <0.05, which means that there is a relationship between knowledge and attitude with adherence to the use of masks in the elderly. It can be concluded that most of the elderly do not have good knowledge and attitudes towards compliance with the use of masks in preventing the transmission of COVID-19.