Currently, the development of the industry is increasing rapidly due to the implementation of many infrastructure projects. Indeed, each industry has great risks. The drilling industry is one of the industry sectors that have a large risk of work accidents. The risk of work accidents can cause a decrease in productivity, so that it is important to minimize the impact of work accident risks. Oil Drilling Companies have projects throughout Indonesia, including in West Java province. The oil drilling project in this province implemented the 'Salam Lima Jari' program to reduce workplace accidents. Before this program, the number of work accidents was high in 2009-2014, that the company initiated to implement this program from 2015 to the present to reduce workplace accidents. This study aims to identify workers' knowledge and measure the effectiveness of the 'Salam Lima Jari' program applied in reducing workplace accidents in the oil drilling company in the West Java project. This quantitative study used a cross-sectional design involving 69 workers of the project. The data were collected using a questionnaire. The results showed a relationship between knowledge and the 'Salam Lima Jari' program on reducing work accidents at the oil drilling company of the West Java project with a p-value of <0.05. The relationship is significant with the knowledge correlation value of -0.670, and the correlation value of -0.0699 is considered in the strong correlation category in reducing work accidents in oil drilling companies.